Cosmetic Injectables

At Dermatology Institute of Southwest Florida, we specialize in a variety of cosmetic injectables and dermal fillers designed to help smooth wrinkles, restore lost volume, and reduce the signs of aging in the face, neck, and hands.

How does aging affect the skin?

As we grow older, the appearance, tone, and texture of our skin are affected by both intrinsic and external factors. Aging skin produces less of the natural proteins and sugars that help to keep the skin looking young and healthy. At the same time, environmental factors and lifestyle choices (such as sun damage and smoking), can hasten the breakdown of key skin components.

Over time, once abundant stores of collagen (which provides structural support and firmness), elastin (which provides elasticity), hyaluronic acid (which helps to keep the skin hydrated), and natural fat (which provides youthful fullness) are slowly depleted. As the skin becomes thinner, dryer, and less elastic, it will begin to sag, allowing wrinkles and deep creases to form. Areas of lost volume can make the face appear hollow and gaunt, and once smooth transition zones between the eyes, cheeks, nose, and lips can become more pronounced as soft tissue volume dissipates.

How do cosmetic injectables reduce the signs of aging?

Cosmetic injectables can help temporarily reduce the signs of aging in the skin, leaving you looking younger and more refreshed. There are a wide variety of cosmetic injectables that work in different ways to help smooth lines and wrinkles, while replacing lost structure and volume. These include:

  • Neurotoxins (BOTOX© , Dysport®, and XEOMIN®), which relax the muscles that cause dynamic wrinkles
  • Hyaluronic acid fillers (Perlane®, Juvéderm®, Restylane®, Belotero®, Voluma™ XC), which help to restore lost volume
  • Collagen stimulators (Sculptra®, RADIESSE®), which help to restore the underlying structure of the skin






BOTOX® COSMETIC (onabotulinumtoxinA) and DYSPORT® (abobotulinumtoxinA) and XEOMIN® (incobotulinumtoxinA)

A natural, purified protein

Up to 4 months

Into muscles that cause wrinkles

Frown lines between the brows (glabellar lines); forehead creases; crow's feet; lines around the mouth, nose, jaw, chin, and neck; excessive sweating in the underarms, hands, and feet.


Hyaluronic acid

Up to 1 year

Into mid to deep dermis

Facial wrinkles and folds such as smile lines, vertical lip lines, lines in the corner of the mouth, marionette lines, and crow's feet.


Hyaluronic acid

Around 6 months

Into the mid dermis

Nasolabial folds, cheeks (in younger patients), marionette lines, hollows under the eyes, lip enhancement, lip borders, lines around mouth, corners of the mouth, philtrum (vertical groove between upper lip and nose), chin, back of hands, and temples.


Hyaluronic acid

Around 6 - 9 months

Into the mid to deep dermis

Deeper facial folds and wrinkles, nasolabial folds (smile lines), cheeks (upper and lower), marionette lines, acne scarring, chin augmentation, eyebrow lift, corners of the mouth, facial fat loss, hands, temples, and jowls.


Hyaluronic acid

Up to 2 years

Into mid to deep dermis

Hollows in the mid-face and cheek area.


Calcium-based microspheres (calcium hydroxylapatite)

Around 9 -12 months

Into the mid to deep dermis

Nasolabial folds (smile lines), cheeks (upper and lower), chin, jaw line, nose, acne scars, depressed scars, oral commissures, temples, eyebrows, earlobes, and hands.


Poly-L-lactic acid

Up to 2 years after an average of 3 treatment sessions over the course of several months

Into deep dermis and areas of depleted tissue volume

Full facial filling, correction of facial fat loss, deep nasolabial folds, marionette lines, hands, and hollowed temples.


Which cosmetic injectable is right for me?

Not only do the various fillers work differently, they may also be best suited for injection in different facial areas, as well as at diverse depths. Understanding when and where to use specific fillers is vital to achieving the best results. As a board-certified dermatologist with expertise in cosmetic dermatology and facial rejuvenation, Dr. Adam S. Greenberg understands not only how each filler works individually, but also how they can be used synergistically as part of advanced layering techniques to provide the most youthful and natural-looking results. For example, Dr. Greenberg may elect to use one filler in the deep dermis to provide structural foundation, another in the mid-dermis to replace lost volume, and a superficial filler to help smooth away surface lines and wrinkles. Dr. Greenberg will meet with you to discuss your goals and help you determine the filler, or combination of fillers, best suited to your specific needs.

What areas can cosmetic injectables treat?

Cosmetic injectables can be used in a wide variety of places for effective facial contouring and rejuvenation. Certain fillers may also be used to reduce the signs of aging in the lips and hands. Some common treatment areas include:

  • Glabellar lines (vertical lines between the brows)
  • Nasolabial folds (“parenthesis lines” between the nose and mouth)
  • Peri-orbital lines (around the eyes)
  • Temporal hollows (on the temples)
  • Tear trough/nasojugal groove
  • Nasal defects
  • Malar enhancement (upper cheeks)
  • Nasal tip
  • Full facial filling (to combat lipoatrophy)
  • Submalar (lower cheeks)
  • Marionette lines
  • Lips
  • Radial lip lines
  • Lip border
  • Chin
  • Acne or trauma scarring
  • Oral commissure (sides of mouth)
  • Mental crease (between lips and chin)
  • Jaw line contouring
  • Hands
  • Prominent neck bands

While most cosmetic injectables may be used in many of these areas, the chart below indicates the most common treatment areas for each injectable. Many of the common treatment areas mentioned in the chart describe off-label uses. 

Cosmetic Injectables FAQ

The versatility, convenience, and measurable results of injectable dermal fillers make them exceedingly popular for all sorts of patients. Today's dermal fillers are just as safe and effective as ever, with millions of men and women around the world using them to reduce wrinkles and replace volume each year. Despite their popularity, prospective patients still have a lot of questions about these treatments. Here, find our answers to some of the ones we hear most often about dermal fillers at our Venice practice.

If you have more questions or are ready to get started, visit the Dermatology & Laser Institute of Southwest Florida. You can request a consultation online or call (941) 488-5300. When you schedule a consultation for cosmetic procedures, you will also receive a customized "Total Skin Rejuvenation" plan to help you maintain a beautiful complexion.

Aren't all dermal fillers basically the same?

No. Although dermal fillers are all gels that are injected under the surface of the skin to add volume, many of them use different active ingredients and come in different formulations that make them more appropriate for different areas of the face. For example, JUVÉDERM® and JUVÉDERM VOLUMA™ XC both have the same active ingredient, hyaluronic acid, which helps skin stay hydrated and firm. But JUVÉDERM was developed specifically to alleviate the lines and wrinkles of the lower face, while JUVÉDERM VOLUMA XC's thicker, more durable formula makes it more appropriate for adding volume to the cheeks. Dr.Greenberg, and our medical staff know how to strategically administer the right fillers to the right areas to yield exceptional results.

What is the difference between BOTOX® Cosmetic and dermal fillers?

Although dermal fillers and BOTOX Cosmetic are both injectable treatments that are used to reduce the appearance of wrinkles, they work in very different ways. As their name implies, injectable fillers use an ingredient to physically fill in wrinkles from below the skin's surface, effectively reducing their appearance. BOTOX Cosmetic and Dysport® both use a purified form of the botulinum toxin to temporarily relax the muscles that cause "dynamic" wrinkles (the wrinkles that occur when we make facial expressions), such as crow's feet, to form. When used strategically, BOTOX Cosmetic and dermal fillers can both create beautiful outcomes.

Who is a good candidate for a dermal filler treatment?

These products work well and are safe for nearly anyone who is interested in erasing wrinkles around the face or adding volume to the lips, cheeks, or under-eye hollows. Most of the fillers we use are made from ingredients that are found naturally in the body. For people who have allergies or sensitivities to any of the ingredients in fillers, we may take extra precautions. During your initial consultation for Sculptra® Aesthetic, RADIESSE®, JUVÉDERM, VOLUMA XC, or Restylane®, Perlane®, BELOTERO®, at our practice, Dr.Greenberg will review your medical history and help you determine whether dermal fillers are right for you.

What happens to the dermal filler ingredients as they wear off?

Dermal fillers are not meant to be permanent. Depending on the type of filler used, as well as its placement, the results of a treatment can last between several months and 2 years. The ingredients in dermal fillers gradually break down and filter out of the body through normal metabolic processes.

Sculptra® Aesthetic, a dermal filler that uses poly-L lactic acid, comes with the added the added benefit of promoting collagen growth within the skin. Over time, the poly-L lactic acid is flushed out of the body while the new, natural collagen stays behind.

Can I combine a dermal filler treatment with another procedure?

Yes! At the Dermatology & Laser Institute of Southwest Florida, we often recommend a combinational approach to help patients resolve several aesthetic concerns at once. It's perfectly safe to "mix and match" dermal fillers or have them administered in conjunction with BOTOX Cosmetic or Dysport in a procedure called a "liquid facelift". Our team look forward to helping you find the right options to reveal your most beautiful skin.

How can I make my results last as long as possible?

Although dermal fillers aren't permanent, they can provide many months of noticeable improvement. The longevity of a dermal filler treatment is highly dependent on the type of filler administered, as well as your own unique anatomy. The best thing you can do to preserve your results is to follow your practitioner's instructions closely. Although there is no significant downtime required after a procedure, you may need to refrain from touching the injection site or temporarily avoid certain substances, such as alcohol. Prior to your procedure, we'll help you understand what to expect from your results, as well as how to maintain them for as long as possible.

How can I find out more about cosmetic injectables?

The Dr.Greenberg will be happy to meet with you to discuss cosmetic injectables treatment. Please call our office at 941-488-5300, or make an appointment online for a personal consultation.

When you schedule a consultation for cosmetic procedures, you will also receive a customized "Total Skin Rejuvenation" plan to help you maintain a beautiful complexion.



  • Subscribe
    Join Our Mailing List
    Contact Info

    1415 East Venice Avenue
    Venice, Florida 34292

    (941) 488-5300